Located near UPMC Horizon – Greenville, Crossroads Treatment Center offers outpatient opioid treatment for clients across Mercer County, accepting Medicaid, Medicare, and most commercial insurance. On-site parking is available. Treatment Methods Treatment begins with a clinical assessment to guide the appropriate approach. Crossroads Greenville offers medication-assisted treatment (MAT) using Sublocade, Brixadi, and Vivitrol (injections), as well as Buprenorphine (prescription). Clients participate in care coordination to help them meet their social and medical needs, available in person or virtually. Hepatitis C treatment is also available at Crossroads.


